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Toradol (Ketorolac)

You’ve seen them on the streets: huge human beings, rolls of fat enclosed in oversized clothing. They weigh 250 pounds, 300 pounds, even 400 pounds. Sometimes they elicit hurtful smirks from others.
Lourie Greenblatt, 57, of Manhattan, weighed 267 pounds. “People in restaurants stare at me in the rudest possible way,” she says. “It makes me feel just horrible.”
Our national obsession with weight is such that a hoaxer easily fooled several reporters for radio and TV stations, newspapers, and wire services when he said he’d formed a “fat squad” whose agents purportedly were hired to trail dieters and keep them honest.
Doctors define as “morbidly obese” individuals whose weight reaches 100 pounds more than the average listed by insurance tables for their size and age. Morbidly obese people fall prey to sudden death from heart attack, to stroke, and to high blood pressure, diabetes, arthritis, kidney disease, swollen ankles, infection, and sleep apnea, a condition in which they stop breathing during sleep. Sleep apnea can trigger heart arrest or leave victims so tired they can’t stay awake during the day.
But more than the physical risk, the morbidly obese often become social cripples. Some employers won’t hire them. They find travel difficult because seats are too small. They don’t visit friends and relatives, fearing they’ll sit on furniture and break it.
Almost all of these too-fat people have tried to diet to lose those killer pounds, but few have succeeded. About 95 percent of those who lose large amounts of weight regain it.
But doctors are making progress against gross, deadly obesity. They have developed surgical procedures to stifle appetite – risky but successful in two of three morbidly obese patients, depending on the surgery. They also prescribe diets very low in calories-about 400 to 800 a day. Patients on the regimen enjoy a success rate similar to that of the surgery, but this approach also is risky, and the relapse rate is higher.
Doctors have other new drugs and techniques now under intensive study:
• Balloon treatment. The patient swallows a balloon to keep the stomach feeling full. As the balloon inflates and as the patient eats, very little room is left in the stomach to accommodate more food. Although this creative approach seemed promising at first, most doctors who tried it did not seem to achieve the same weight reduction as the inventors of the balloon did.
• Drugs that suppress appetite. Promising medicines are on the horizon but not yet for sale. Some of these drugs may be addicting.
• Drugs that help burn energy
• Drugs that hinder fat absorption. Again, the safety and efficacy of this treatment need to be established.
• Psychological methods that help overcome the desire to eat. A psychologist can teach a person to control eating habits. For example, Dr. Thomas A. Wadden, assistant professor of psychology at the University of Pennsylvania School of Medicine in Philadelphia, has helped the morbidly obese lose weight with behavior modification alone. One patient, Joan Wozniak 58, of Stratford, New Jersey, lost 50 pounds by keeping a food diary, exercising, and following Dr. Wadden’s psychological tips. Powerful as such methods are, the chances for long-term success are low for the hugely overweight.

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