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Orap (Pimozide)

Angiotensin Converting Enzyme (ACE) inhibitors lower high blood pressure by relaxing the tense walls of tight arteries. Capoten and Renitec were a great breakthrough in the management of high blood pressure when they first appeared on the scene in the late eighties. They were touted as effective agents – virtually side effect free. Soon up to 30 per cent of people taking ACE inhibitors complained of a chronic cough. Further side effects became known which were only visible in the test tube.
The ACE inhibitors caused kidney damage, and deaths occurred amongst a small group of immune suppressed people taking ACE inhibitors, with other medication. In spite of the potential for these widely reported side effects, doctors are avid prescribers of ACE inhibitors. Happily this group of drugs reduces the incidence of death amongst people with heart failure by up to 40 per cent. The wise patient taking ACE inhibitors reminds their doctor to take blood samples for both kidney function tests and a full blood count every six to twelve months.
Antihistamines, Blood Pressure, Heart Failure, Vasodilators.
Home Remedies
If a “Capoten Cough” complicates the use of ACE inhibitors a dose reduction usually deals with the problem. Occasionally complete withdrawal of the drug is in order. Evidence is accumulating that the non sedating antihistamines and some of the Non Steroidal Anti-inflammatory Drugs (NSAIDS) inhibit a “Capoten Cough”. Prescribing a second drug to counteract the side effects of a first one is a deplorable practice. Doctors should avoid it where ever possible.

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