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Colospa (Mebeverine)

All fat persons dream of taking a pill that will magically cause pounds to melt away. A dozen pharmaceutical companies are working hard to turn that dream into reality – and cash.
“We are trying to design molecules that intervene in the body’s regulation of fat storage and food consumption,” says Ann C. Sullivan, director of pharmacology and chemotherapy for Hoffmann-La Roche Inc., in Nutley, New Jersey. The pharmaceutical companies are now testing some of these molecules in human beings. Preliminary results indicate that they might work. The experiments are in their infancy but promising. The drugs being tested could help you lose weight in three ways:
1. Appetite suppression. One stomach hormone, released while eating, has been found to mildly suppress the appetite. But so far, an increased supply can be given by injection only.
Another group of drugs acts on a brain chemical called serotonin. Preliminary tests on obese patients resulted in weight loss.
Naloxone, a drug used to treat heroin users, blocks the brain’s reaction to opium products. Tests show it also has some effect in suppressing the appetite of persons who do not use such narcotics.
2. Fat and carbohydrate absorption. Fat forms if the digestive system sends an excess of fats and sugars into the blood. Several drugs block either fat or carbohydrate absorption.
3. Stepping up energy expenditure. Since the obese person’s body burns energy very efficiently, it simply uses fewer calories to maintain itself during weight loss. And as the body’s fuel-burning system burns less and less energy, weight loss becomes harder and harder. (It also results in the obese person feeling cold while dieting.) To counter this, three drug companies are testing compounds that might increase body energy use. If successful, they can step up the number of calories burned.
So far, none of the drugs being tested is available. Until they’re proved safe and marketed, you’ll have to lose weight without the aid of anti-fat pills.

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